Results 41 to 50 of about 31,494 (256)
Nauka ta progres transportu, 2016 Purpose. The paper aims to develop rating models and related information technologies designed to resolve the tasks of strategic planning of the administrative and territorial units’ development, as well as the tasks of multi-criteria control of ...
O. M. Pshinko, V. V. Skalozub
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Analysis of the Operational Process based on the Balanced Scorecard
Учёт. Анализ. Аудит, 2019 Subject. In modern conditions the organization’s customer strategy must ensure the maximum long-term efficiency in the operational activity which makes the problem of improving analytical support of operational process management from strategic viewpoint
Svetlana Aronovna Boronenkova +1 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Land and Property Complex: its Essence and Approaches to Management
Вестник Российского экономического университета имени Г. В. Плеханова, 2022 The article studies the essence of the economic category ‘land-property complex’ in respect to a business entity – enterprise, analyzes theoretical approaches to its management and shows approbation of methodology of strategic management at the ...
E. A. Matushevskaya
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A comprehensive review on strategic purchasing of diagnostic imaging services
Journal of Education and Health PromotionDiagnostic imaging services are one of the rapidly growing services in the healthcare industry and policymakers consider containing the cost of such services as a way to reduce the total cost of healthcare services. This study aimed to identify the components influencing the implementation of strategic purchase of diagnostic imaging services.
Abdollah Soltan-Tajian +2 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Strategic diagnostics in the system of controlling the financial results of the enterprise
Naukovyi Visnyk Natsionalnoho Hirnychoho Universytetu, 2022 Purpose. To create a mathematical model and approaches for the formation of optimal management actions on the basis of strategic diagnostics data and to use them to form an effective algorithm of strategic diagnostics in the system of controlling the financial results of the enterprise. Methodology.
H Silakova +4 more
openaire +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source