Results 61 to 70 of about 1,672,360 (286)
The global rise of antimicrobial resistance (AMR), manifesting as multidrug-resistant, extremely drug-resistant, and pandrug-resistant pathogens, is causing morbidities which are alarmingly translating to mortalities.
Maargavi Singh +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A comprehensive review on strategic purchasing of diagnostic imaging services
Diagnostic imaging services are one of the rapidly growing services in the healthcare industry and policymakers consider containing the cost of such services as a way to reduce the total cost of healthcare services. This study aimed to identify the components influencing the implementation of strategic purchase of diagnostic imaging services.
Abdollah Soltan-Tajian +2 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Acknowledgement to Reviewers of Diagnostics in 2017
Peer review is an essential part in the publication process, ensuring that Diagnostics maintains high quality standards for its published papers.[...
Diagnostics Editorial Office
core +1 more source
A Bayesian look at diagnostics in the univariate linear model [PDF]
This paper develops diagnostics for data thought to be generated in accordance with the general univariate linear model. A first set of diagnostics is developed by considering posterior probabilities of models that dictate which of k observations form a ...
Guttman, Irwin, Peña, Daniel
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Acknowledgement to Reviewers of Diagnostics in 2013
The editors of Diagnostics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in ...
Diagnostics Editorial Office
core +1 more source
3D-Printed Biosensor Arrays for Medical Diagnostics
While the technology is relatively new, low-cost 3D printing has impacted many aspects of human life. 3D printers are being used as manufacturing tools for a wide variety of devices in a spectrum of applications ranging from diagnosis to implants to ...
Mohamed Sharafeldin +2 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

