Results 81 to 90 of about 31,494 (256)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Diagnostics of enterprise bankruptcy occurrence probability in an anti-crisis management: modern approaches and classification of models

Vìsnik Žitomirsʹkogo Deržavnogo Tehnologìčnogo Unìversitetu: Ekonomìčnì Nauki, 2015
Diagnostics of enterprise bankruptcy occurrence probability is defined as an important tool ensuring the viability of an organization under conditions of unpredictable dynamic environment.
I.V. Zhalinska
doaj  

CARDIAC STENTING IN DEXTROCARDIA- AN APPROACH TO A RARE HEART ANOMALY: A CASE-BASED REVIEW

Anti-Aging Eastern Europe
Dextrocardia with situs inversus, often called mirror dextrocardia, is an uncommon congenital heart defect where the heart’s apex points to the right side. The success of percutaneous coronary intervention (PCI) may contribute to its impact on individual
Darkhan Suigenbayev, Issabek Kerimkulov, Akerke Auanassova, Zhanibek Orazaly, Galiya Assanova   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Ocular Clues to Liver Disease: A Strategic Diagnostic Lens

Diseases
Background/Objectives: Hepatic diseases frequently present with ocular manifestations that aid diagnosis, provide prognostic data, and guide therapy. Despite the clear utility of the liver–eye axis, the literature lacks reviews that categorize these manifestations by etiology.
Muhammad Dahshan, Hassan Dahshan, Ayhan Basoglu, Huseyin Kadikoy   +3 more
openaire   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Strength, weakness, opportunities and challenges (SWOC) experience of histopathology image analysis, enhanced by artificial intelligence

Journal of Oral Biology and Craniofacial Research
Artificial intelligence (AI) is reshaping the landscape of oral cancer diagnosis through the analysis of digital imaging. By promoting early detection, enhancing diagnostic precision, and enabling personalised treatment approaches, AI holds the potential
Narendra Nath Singh, Ankita Tandon, Pavithra Jayasankar   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Enhancing diagnostic innovation by leveraging the co-creation approach

Journal of Pathology Informatics
Digital innovation in precision diagnostics requires addressing complex challenges, such as implementation, adoption, equity, and sustainability.
Jochen K. Lennerz, Alexandra Farfsing, Tim-Rasmus Kiehl, Sven Perner, Joost van Duuren, Marleen Christ, Jan W. Farfsing   +6 more
doaj   +1 more source