Results 91 to 100 of about 57,879 (291)

The Effectiveness of the Utilization and Distribution of Productive and Consumptive Zakat in the 5 Programs of BAZNAS Batam City (A Case Study of BAZNAS Batam City)

Indonesian Interdisciplinary Journal of Sharia Economics
This research investigates the effectiveness of the utilization and distribution of zakat across five key programs of BAZNAS Batam City: Batam Makmur, Batam Cerdas, Batam Sehat, Batam Taqwa, and Batam Peduli.
Muhammad Fazmi, Yayat Sujatna
doaj   +1 more source

Causal Loop Model for Problem of Traffic Accident: The System Dynamics Approach [PDF]

چشم‌انداز مدیریت صنعتی, 2017
Due to the high rate of Traffic accident and death toll in Iran, recently the case has altered into a major national hitch.  Through System Dynamics point of view and examining significant factors like the yearly death toll of vehicle accidents in Iran ...
Masood Rabieh, Hedayat Salari, Mohammad Mehdi Karami, Mostafa Ziyaei, Azizolah Yasoubi   +4 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Generating Value from Whole-Life Solutions – A New Opportunity for the UK Rail Industry [PDF]

, 2009
The UK government has started to demand a “whole-life, whole-system” view of new contracts within the UK rail industry; requiring the industry to transform the way it does business in order to deliver this new paradigm. This paper describes the work of a
Clayton, Richard J., Richard J. Clayton (7204499), Lovell, Jeremy, Samir Dani (5826068), Chris Backhouse (1249161), Backhouse, C.J., Dani, Samir, J. Lovell (7207262)   +7 more
core  

The concept of an architectural solution for the service intended to build an enterprise strategy map

Вісник Національного технічного університету "ХПÌ": Системний аналіз, управління та інформаційні технології, 2017
The article examines an architectural solution of a software application for building an enterprise strategy map. It gives a short review of existing software products at the IT-market, which is used in strategic enterprise performance management.
Valentina Volodymyrovna Moskalenko, Yuriy Stanislavovich Berezenko   +1 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

COMPETENCY-BASED APPROACH TO PERSONNEL MANAGEMENT AS THE KEY TO EFFECTIVE ORGANIZATIONAL DEVELOPMENT IN THE CONDITIONS OF MODERN CHALLENGES

Економіка та суспільство
The article examines the evolution of approaches to personnel management – from administrative-bureaucratic models to modern strategic human resources management, based on the competency approach.
Ольга Майстренко, Вадим Васюк   +1 more
doaj   +1 more source

Theme trends and knowledge structure on choroidal neovascularization: a quantitative and co-word analysis

BMC Ophthalmology, 2018
Background The distribution pattern and knowledge structure of choroidal neovascularization (CNV) was surveyed based on literatures in PubMed. Methods Published scientific papers about CNV were retrieved from Jan 1st, 2012 to May 31st, 2017.
Fangkun Zhao, Bei Shi, Ruixin Liu, Wenkai Zhou, Dong Shi, Jinsong Zhang   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source