Results 71 to 80 of about 9,722,264 (303)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Regional planning guideline review : using MOLAND as part of the strategic environmental assessment process [PDF]

, 2009
The urban fabric of the Greater Dublin Area (GDA) has expanded rapidly over the past 20 years. In an effort to coordinate development across the region the “Strategic Planning Guidelines for the Greater Dublin Area” were introduced in 1999.
Brennan, Michael, Carty, John, Shahumyan, Harutyun, Walsh, Cormac, Williams, Brendan, Convery, Sheila   +5 more
core   +1 more source

Applying sustainability assessment models [PDF]

, 2005
Three sustainability assessment models are applied to a major Australian resource proposal- the Gorgon gas development. 'Environmental impact assessment (EIA)-driven integrated assessment' resulted in significant environmental resources being 'traded ...
Pope, Jennifer, Annandale, D., Morrison-Saunders, A.   +2 more
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Assessment (Social Environmental Strategic Assessment) Study in the Coastal Area of Guinea-Bissau

, 2023
Consulenza scientifica, per la società SETIN srl (Roma), per gli aspetti relativi alla pianificazione urbanistica locale e generale, alla componente paesaggistica e storico culturale, e agli aspetti legati al cambiamento climatico finalizzati alla ...
Rosalba D'Onofrio, Elio Trusiani, Giorgio Caprari   +2 more
core   +1 more source

Handbook of Strategic Environmental Assessment [PDF]

Journal of Integrative Environmental Sciences, 2012
Handbook of Strategic Environmental Assessment, edited by Barry Sadler, Ralf Aschemann, Jiri Dusik, Thomas B. Fischer, Maria R.
openaire   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Developing and testing a policy environmental assessment checklist for biodiversity conservation [PDF]

, 2008
Strategic environmental assessment (SEA) and policy environmental assessment (PEA), the term used to describe the application of SEA at the policy level, are widely accepted as means of including environmental concerns in decision-making.
Genter, S., Moore, S.A., Bailey, J.
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Aspectos ambientais no Plano Nacional de Logística e Transporte do Brasil

Desenvolvimento e Meio Ambiente, 2015
The Brazilian government has been heavily investing in transportation infrastructure. According to environmental laws, this kind of enterprise must do an environmental impact assessment (EIA). However, the EIA is a regulatory measure applied post-project,
Silvana Zioni, Simone Rodrigues de Freitas   +1 more
doaj   +1 more source