Results 81 to 90 of about 818,638 (305)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Potential of Strategic Environmental Assessment to Improve Urban Planning in Sierra Leone. [PDF]

Int J Environ Res Public Health, 2021
Mabey PT, Li W, Sundufu AJ, Lashari AH.
europepmc   +1 more source

Analysis for biotechnology innovations using Strategic Environmental Assessment (SEA): [PDF]

" Meeting the food needs of the world's growing population while reducing poverty and protecting the environment is a major global challenge. Genetically modified crops appear to provide a promising option to deal with this challenge.
Birner, Regina, Falck-Zepeda, José, Gaskell, Joanne, Halsey, Mark, Linacre, Nicholas A., Quemada, Hector, Rosegrant, Mark W.   +6 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Regional plan of communal waste management: Methodological approach for the strategic environmental assessment [PDF]

Arhitektura i Urbanizam, 2007
Strategic environmental assessment (SEA) represents one of the most significant instruments for the implementation of environmental protection strategy in the spatial and urban planning.
Josimović Boško, Maričić Tamara
doaj  

Sea Guidelines. A Comparative Analysis: First Outcomes

TeMA: Journal of Land Use, Mobility and Environment, 2014
The European Directive 2001/42/EC (Directive) has introduced the Strategic Environmental Assessment (SEA), a procedure for assessing the effects of certain plans and programs on the environment.
Andrea De Montis, Antonio Ledda, Simone Caschili, Amedeo Ganciu, Mario Barra, Gianluca Cocco, Agnese Marcus   +6 more
doaj   +1 more source

Analysing students' environmental awareness profile using strategic environmental assessment. [PDF]

F1000Res, 2021
Khoiri A, Khoiri A, Sunarno W, Sajidan S, Sukarmin S.   +4 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Integration of strategic environmental assessment (SEA) in motorway/highway planning and construction: A case study for sustainable infrastructure development in Pakistan

NUST Journal of Natural Sciences
Pakistan has constantly prioritized the development of roads and motorways as they are they are reflective of nation’s economic and physical condition.
Syeda Safina Ali, Ayesha Batool
doaj   +2 more sources