Results 81 to 90 of about 86,084 (307)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Aspectos ambientais no Plano Nacional de Logística e Transporte do Brasil

Desenvolvimento e Meio Ambiente, 2015
The Brazilian government has been heavily investing in transportation infrastructure. According to environmental laws, this kind of enterprise must do an environmental impact assessment (EIA). However, the EIA is a regulatory measure applied post-project,
Silvana Zioni, Simone Rodrigues de Freitas   +1 more
doaj   +1 more source

The Potential of Strategic Environmental Assessment to Improve Urban Planning in Sierra Leone. [PDF]

Int J Environ Res Public Health, 2021
Mabey PT, Li W, Sundufu AJ, Lashari AH.
europepmc   +1 more source

Strategic environmental assessment: Effective planning instrument or lost concept

, 2002
After its 'invention' as a fairly clearly defined instrument for assessing the environmental impacts of policies, plans and programmes in the 1980s, at the end of the 1990s SEA appeared more an undefined concept than a clear and effective planning ...
Fischer, Thomas B., Seaton, Kim
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Analysing students' environmental awareness profile using strategic environmental assessment. [PDF]

F1000Res, 2021
Khoiri A, Khoiri A, Sunarno W, Sajidan S, Sukarmin S.   +4 more
europepmc   +1 more source

Planning a SEA change: designing a robust framework for strategic environmental assessment in Nova Scotia

, 2014
Strategic environmental assessment (SEA) provides governments, and other organizations, a method to formally incorporate environmental dimensions into strategic planning and policy evaluation exercises.
Whynacht, Christopher R
core  

Designing a management framework for Strategic Environmental Assessment of urban plans in China

, 2009
Based on the revision of theMethods for Urban Plan Formulation and the Technical Guidelines of Environmental Impact Assessment for UrbanMaster Plan (in draft), this paper proposes a management framework for Strategic Environmental Assessment (SEA) of ...
Ou-Yang, L, Huang, He, Brown, AL, Bao, Cun-Kuan, Gao, Ying-wei, Jiang, Dahe, Brown, Lex, Zhou, Ying-lie, Gao, YW, Huang, H, Zhou, YL, Ou-Yang, Li, Jiang, D, Bao, CK   +13 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Sacrificing Wilderness for Renewables? Land Artificialization from Inadequate Spatial Planning of Wind Energy in Evvoia, Greece

Land
The REPowerEU Plan calls for a massive speed-up of renewable energy, which can undermine nature conservation. We explored the impact of an industrial-scale wind power project planned inside a Natura 2000 site (Special Protected Areas for birds) in the ...
Vassiliki Kati, Konstantina Spiliopoulou, Apostolis Stefanidis, Christina Kassara   +3 more
doaj   +1 more source