Results 121 to 130 of about 10,433,910 (363)

USING STRATEGIC MANAGEMENT STUDY CASES IN ROMANIA [PDF]

open access: yes
The paper discuss the use of study case in the teaching of strategic management and the translation of the method from United States to Romania. Some technical aspects of American experience in strategic management case researching are underlined, with a
Bacanu Bogdan
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Modern approaches to the immunotherapy of Clostridioides difficile

open access: yesЖурнал инфектологии
Clostridioides difficile is a leading cause of diarrhea and pseudomembranous colitis associated with antibiotic therapy. Hypervirulent strains of C. difficile, such as ribotype 027, have high mortality rates. Recurrent C. difficile infection is extremely
K. E. Popruga, V. V. Makarov
doaj   +1 more source

Strategic Approach to Farming Success [PDF]

open access: yes
This paper is an abstract of a new book for farmers launched on April 8, 2005 (Nell & Napier, 2005). The two authors, Wim Nell of South Africa and Rob Napier of Australia, have respectively 28 and 37 years national and international experience in ...
Napier, Robert John, Nell, Wilhelm T.
core   +1 more source

Strategic Leadership Newsletter: Volume 4, Number 2 [PDF]

open access: yes, 2017
Jefferson Strategic Leadership Newsletter reports information relevant to the Jefferson (Philadelphia University + Thomas Jefferson University) Doctor of Management Program in Strategic Leadership (DSL) and its community including personal and ...
Starr, Larry M., PhD
core   +8 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

THE FIRM’S PATRIMONY – AN INTERNATIONAL APPROACH [PDF]

open access: yes
The organization environment is characterized by uncertainty and risk that have an important impact of strategic management. In order to face this problem the managers need to plan their strategies. A useful tool in strategic planning is forecasting, but
Elena DOVAL
core  

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