Results 41 to 50 of about 162,147 (257)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Citizens’ exposure to predominant noise sources in agglomerations

open access: yesNoise Mapping
Environmental noise directive requires Member States to produce and periodically update strategic noise maps for agglomerates in order to evaluate citizens’ noise exposure before the action plan.
Bolognese Matteo   +5 more
doaj   +1 more source

Exploring the use of mobile sensors for noise and black carbon measurements in an urban environment [PDF]

open access: yes, 2012
Mobile measurements have been collected on a bicycle equipped with a global positioning system (GPS) in a few connecting streets in Gent (Belgium). The 1-s sound pressure levels and 1-s black carbon concentrations were measured. In addition, 5 continuous
Botteldooren, Dick   +2 more
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Noise pollution maps in the perimeter of Galati main ports

open access: yesAnnals of "Dunărea de Jos" University of Galaţi: Fascicle XI Shipbuilding, 2017
Noise mapping is one of the modern methods of evaluation of urban acoustic pollution due to the presence of road traffic, rail traffic (train or tram), industrial noise and air traffic.
Costică Hogaș   +2 more
doaj  

A Multi-Observer Based Estimation Framework for Nonlinear Systems under Sensor Attacks

open access: yes, 2019
We address the problem of state estimation and attack isolation for general discrete-time nonlinear systems when sensors are corrupted by (potentially unbounded) attack signals.
Kuijper, Margreta   +3 more
core   +1 more source

Strategic noise map of a major road carried out with two environmental prediction software packages [PDF]

open access: yesEnvironmental Monitoring and Assessment, 2009
The main objective of this study is to analyze the differences found in the results of noise mapping using two of the most popular software techniques for the prediction of environmental noise. The location selected to conduct the comparative study is an area encompassed by the ring road that surrounds the city of Pamplona and on a grid, with a total ...
Arana Burgui, Miguel   +3 more
openaire   +4 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Home - About - Disclaimer - Privacy