Results 61 to 70 of about 6,099,490 (258)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Upaya Cina menjadi Kekuatan Maritim dalam Indian Ocean Rim Association (IORA)
Nation State, 2018 After the economic reform in 1978, China experienced a rapid economic growth. The open door policy adopted on economic reforms succeeded in attracting many foreign investors in the sector of manufacture.
Umi Qodarsasi, Tety Rachmawati
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
THE STRATEGIC RECONFIGURATION OF THE POWER POLES [PDF]
Annals: Series on Military Sciences, 2014 Starting from approaching the aspects of globalism, technological, economical and cultural progress of the contemporary world, the paper focuses on the reconfiguration of the strategic interest of the power hot spots (or power poles), the latest breaking
Sebastian SÂRBU
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
STRATEGIC DEVELOPMENT AND CHALLENGES OF ITS POWER SUPPLY
Вестник Российского экономического университета имени Г. В. Плеханова, 2018 All countries aim at designing the program of strategic development. It is caused both by expectations of the new technological structure deployment and ambitions to retain their positions in the global labour division.
Alexander A. Gajour
doaj +1 more source
Impact of wind power on the unit commitment, operating reserves and market design [PDF]
, 2011 Paper presented at the 2011 IEEE Power and Energy Society General Meeting, San Diego, CA, 24-29 July 2011This article highlights and demonstrates the new requirements variable and partly unpredictable wind power will bring to unit commitment and power ...
Milligan, M. +26 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Other title: Alabama Power Company electric transmission and distribution system
, 1954 Identifies generating plants, substations, types of transmission lines, areas served, and areas served by other ...
Alabama Power Company.
core +1 more source