Results 71 to 80 of about 6,099,490 (258)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Alabama Power Company electric transmission and distribution system
Identifies generating plants, substations, types of transmission lines, areas served, and areas served by other ...
Alabama Power Company.
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Strategic power indices: Quarrelling in coalitions [PDF]
While they use the language of game theory known measures of a priory voting power are hardly more than statistical expectations assuming voters behave randomly.
László Á. Kóczy
core +2 more sources
Crisis, Deterrence & Diplomacy: Pakistan’s Rising Middle Power Profile after India’s 2025 Aggression
This paper examines how India’s May 2025 military aggression, culminating in Operation Sindoor, became a strategic catalyst that elevated Pakistan’s geopolitical profile and consolidated its emergence as an emerging middle power despite clear asymmetry ...
Waleed Rasool
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Strategic Thinking, Strategies and Power in Contemporary Society
Strategy, as a reflection in a more or less military context, has been and remains a permanent feature of human experience both historically and today.
Nicolae-Florin Prunău
doaj
This PR pamphlet explains what BPA (Bonneville Power Administration) is (a Federal agency with a Northwest focus). It plays a role in balancing river uses; power revenues pay BPA costs; renewable resource aspects are discussed; fish and wildlife ...
United States. Bonneville Power Administration.
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Integrated energy systems (IESs) require carbon-policy designs that are not only cost-effective under representative conditions but also robust under uncertainty and feasible in long-term execution.
Fei Zhao, Shumei Chu
doaj +1 more source

