Results 151 to 160 of about 819,854 (302)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Advancing protein engineering via organic chemistry. [PDF]

Commun Chem
Nithun RV, Singh M, Baransi A, Jbara M.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Rejection or support? research on labor participation strategy of older adults based on three-party evolutionary game. [PDF]

PLoS One
Shen Y, Zhong Y, Sun F.
europepmc   +1 more source

Noncooperative Foundations of Stable Sets in Voting Games. [PDF]

This note investigates the noncooperative foundations of von Neumann-Morgenstern (vN-M) stable sets in voting games. To do so, we study subgame perfect equilibria of a noncooperative legislative bargaining game, based on underlying simple games.
Vincent Anesi
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The dynamic interactions of policy instruments in China's community sports governance: a tripartite evolutionary game analysis. [PDF]

Front Public Health
Yuan J, Liu Y, Luo X.
europepmc   +1 more source

TURKEY'S DILEMMA AND STRATEGIC STABILITY

AUSTRAL: Brazilian Journal of Strategy & International Relations
Este artigo trata das Relações Internacionais da Turquia e do impacto de suas escolhas no Sistema Internacional (SI) nesta nova era marcada pela volta da competição entre as potências terrestres. Especificamente, discute-se acerca do dilema turco, reduzido à duas possíveis linhas de conduta: entre a adesão a um comportamento revolucionário, ou a ...
de Vasconcellos Esquia, Jean-Pier, Quedi Martins, José Miguel   +1 more
openaire   +1 more source

A Unified Approach to Information, Knowledge, and Stability [PDF]

Within the context of strategic interaction, we provide a unified framework for analyzing information, knowledge, and the "stable" pattern of behavior.
Xiao Luo, Yi-Chun Chen
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source