Results 61 to 70 of about 4,753,726 (342)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Nuclear Weapons and China’s National Security: Consistency, Evolvement and Risk Management
Journal for Peace and Nuclear DisarmamentThis paper examines the evolving role of nuclear weapons in China’s national security policy, emphasizing the interplay between consistency, adaptation and nuclear risks amidst changing global dynamics.
Qiyang Niu
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In Search of Stability NATO's Strategic Crossroads; Strategic Insights: v.2, issue 5 (May 2003) [PDF]
, 2003 This article appeared in Strategic Insights (May 2003), v.2 no.5World War I saw the end of the empires that had dominated the European political scene for centuries and it cut short the lives of over ten million human beings.
Wilson, Brendan
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The development of logistics approach in business organizations fisheries
Путеводитель предпринимателя, 2020 The article reveals the possibility of using a logistic approach as a tool for strategic stability of the production sector of business structures and management of innovation development.
doaj
Strategic Stability in the 21st Century [PDF]
, 2020 Strategic Stability in the 21st Century needs to be rethought in order to involve all relevant actors and to meet new technological challenges. The USA, Russia, China, and Europe each have different definitions of and perspectives on Strategic Stability ...
Kühn, Ulrich, Fix, Liana
core +1 more source
Strategic Positioning and Strategic Stability: Does It Matter to Performance?
Revista Ibero-Americana de Estratégia, 2013 This study investigates whether oil multinational oil companies (MNCs) have adopted distinct strategic positioning and whether strategic positioning and firm performance are related. Cluster analysis of 50 firms identified 10 strategic types. Although no statistically significant differences were found in expected future performance on an annual basis,
da Silva, Jorge Ferreira +3 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source