Results 101 to 110 of about 19,017 (302)

Time and Energy Managed Operations (TEMO): Cessna Citation II Flight Trials [PDF]

, 2016
From 9-26 October 2015 the Netherlands Aerospace Centre (NLR) in cooperation with Delft University of Technology (DUT) has executed Clean Sky flight trials with the Cessna Citation II research aircraft.
Bussink, Frank, Dalmau Codina, Ramon, Prats Menéndez, Xavier, Verhoeven, Ronald   +3 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

THE COMPETITIVE POSITIONIG OF THE SME'S ON THE MARKET [PDF]

Having in view at the same time the possibilities identified for the development of the competitivity of the Romanian SMEs in order to face the new challengens and the use of the opportunities to operate on the inner market as well as the on the level of
Pop (Bandi) Ramona
core  

Anthropic pressures on Nature 2000 Sites: recommendations and monitoring criteria for the pollution emergency response activities within the Orbetello lagoon [PDF]

, 2007
L’elevato valore naturalistico e socioeconomico di un Sito Natura 2000 richiede che tutte le attività antropiche che si svolgono al suo interno (es.
Ausili, A., Barbara, W., Cappucci, S., De Propris, L., Gabellini, M., Giovanardi, F., Girardi, R., Mumelter, E., Onorati, F., Russo, S., Tornato, A., Trama, V., Trinchera, G.   +12 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

THE ROLE OF URBAN TOURISM IN THE STRATEGICAL DEVELOPMENT OF BRASOV AREA [PDF]

The present work proposes to analyze the importance of tourism in the development of an urban area. Taking into consideration the areas with touring potential existing in Romania, we chose Brasov, whose variety of resources in this field, can offer ...
Razvan-Andrei CORBOS, Ruxandra Irina POPESCU   +1 more
core  

Business and Information Technology Alignment Measurement -- a recent Literature Review

, 2019
Since technology has been involved in the business context, Business and Information Technology Alignment (BITA) has been one of the main concerns of IT and Business executives and directors due to its importance to overall company performance ...
A Etien, Ahmad Nadali, B Raadt van der, D Minoli, D Sledgianowski, D Őri, E Umoh, J Luftman, J Luftman, J Luftman, J Luftman, JA Zachman, JC Henderson, JN Luftman, K Doumi, L Cuenca, L-H Thevenet, M El-Mekawy, M Khaiata, M Sarandis, O Avila, O Avila, O Avila, P Mongeon, R Wagter, S Spewak   +25 more
core   +1 more source