Results 141 to 150 of about 8,270,702 (310)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Transparency in Meat Production – Consumer Perception at the Point of Sale [PDF]
As a result of a large number of food scandals, societal interest in transparency in the food sector has grown considerably. Deficits have been discovered, which new legal frameworks of the EU and the German legislative body have attempted to address ...
Deimel, Mark
core +1 more source
Improving Our Understanding of Moderation and Mediation in Strategic Management Research
, 2017 Herman Aguinis +2 more
semanticscholar +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
ADDED VALUE IN ALIGNMENT OF EQUIPMENT CHARACTERISTICS AND ORGANIZATIONAL GOALS
Croatian Operational Research Review, 2012 This paper examines added value in the alignment of equipment characteristics and strategic organizational goals as an important activity for the execution of organizational tasks.
Irena Peharda, Tihomir Hunjak
doaj
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Environmental Health Education: From Museum Specimens and Math Word Problems to Virtual and Augmented Reality. [PDF]
Environ Health Insights, 2021 Maipas S +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Sugarcane maturity estimation through edaphic-climatic parameters
Scientia Agricola, 2004 Sugarcane (Saccharum officinarum L.) grows under different weather conditions directly affecting crop maturation. Raw material quality predicting models are important tools in sugarcane crop management; the goal of these models is to provide productivity
Scarpari Maximiliano Salles +1 more
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