Results 41 to 50 of about 18,665 (261)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Sensemaking reconsidered : towards a broader understanding through phenomenology [PDF]

open access: yes, 2020
We develop a typology of sensemaking in organizations that reconsiders existing sensemaking research by providing a more coherent and integrative conceptualization of what defines sensemaking and how it is connected with organizing.
Sandberg, Jörgen, Tsoukas, Haridimos
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Entrepreneurship as nexus of change: the syncretistic production of the future [PDF]

open access: yes, 2007
This paper deals with the issue of how the future is created and the mechanisms through which it is produced and conceived. Key to this process appears to be social interaction and how it is used to bring about change.
Anderson, A R   +2 more
core  

Developing a dominant logic of strategic innovation [PDF]

open access: yes, 2013
Purpose: This paper aims to lay the foundations to develop a dominant logic and a common thematic framework of strategic innovation (SI) and to encourage consensus over the field’s core foundation of main themes.
Paroutis, Sotirios   +1 more
core   +3 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Integrating Metacognitive Practice as a Strategy for More Equitable Storytelling in Community-Based Learning

open access: yesPrompt, 2022
Storytelling is a practice which is critical for the communication of lived experience, the development of empathy, and for the creation of a rich sense of collective being.
Marisa Charley
doaj   +1 more source

Management accounting in support of strategy - a strategy as practice perspective [PDF]

open access: yes, 2014
The term Strategic Management Accounting (SMA) was coined in the 1980's to both describe and encourage the development of accounting techniques that addressed strategic decision-making.
Pitcher, GS
core  

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

STRATEGY AS PRACTICE IN THE STRUCTURATIONIST PERSPECTIVE: AN ESSAY ON ONTOLOGY OF STRATEGIC PRACTICE IN ORGANIZATIONS

open access: yesFaces: Revista de Administração, 2013
The Strategy-as-Practice discipline appropriates other theories with converging ontological and epistemological assumptions to build its analytical body, thus this theoretical study offers a discussion on the appropriation of Structurationism Ontology ...
MARCIO LUIZ MARIETTO   +1 more
doaj  

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