How to Deal With Burden of Critical Illness: A Comparison of Strategies in Different Areas of China [PDF]
, 1969 Pengcheng Liu, Liwen Jiang, Chengyue Li
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Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
A Note on Thrifty Strategies and Martingales in a Finitely Additive Setting [PDF]
, 1969 William D. Sudderth
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TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
The HIV Epidemic in Tanzania Mainland:Where have we come from, Where is it Going, and how are we responding? [PDF]
, 2008 AIDS Strategy & Action Plan, (ASAP)
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Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
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Stability of Hold and Postural Control During Static Hold Assessment Can Provide Valuable Information for Biathlon Standing Shooting but Aiming Strategy Should Be Acknowledged. [PDF]
Eur J Sport SciKöykkä M +3 more
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Effect of restricted retail merchandising of discretionary food and beverages on population diet: post-trial follow-up of a pragmatic randomised controlled trial. [PDF]
Lancet Reg Health West PacMcMahon E +12 more
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