Results 161 to 170 of about 6,714,983 (312)

Kenya Youth Agribusiness Strategy 2018-2022

open access: yes, 2018
The MoALF in consultation with the County Governments and development partners have developed the Strategy with a view to increasing meaning and sustainable youth participation in the agricultural sector.

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Kenya National Energy Efficiency and Conservation Strategy 2020

open access: yes, 2020
Energy Efficiency and Conservation is one of the key pillars of sustainable development in Kenya. The government has placed it as one of the priority areas of improvement in its efforts to enhance the quality of life of its citizens.

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Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Isiolo county Procurement Strategy 2025 [PDF]

open access: yes
This Procurement Strategy provides high-level key objectives for the Procurement Team to deliver performance and value creation. The below strategic objectives and activities of the County Government of Isiolo as set out in the County Integrated ...
County Government of Isiolo
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Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Kitui County Fiscal Strategy Paper 2015/2016

open access: yes, 2015
The 2015 Kitui County Fiscal Strategy Paper (CFSP) is the second to be prepared by the county government of Kitui. It addresses the challenges encountered in the implementation of the previous budget as set out in the CFSP 2014.

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