Results 171 to 180 of about 10,984,262 (303)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

(Re)considering Discourses of Risk and Responsibility Through the Lens of Healthism: Interpreting the International Response to a Global Health Strategy for Noncommunicable Diseases. [PDF]

Sociol Health Illn
Brown T.
europepmc   +1 more source

CONTENT MARKETING STRATEGY [PDF]

, 2013
Kurbatova, T., Nechaev, D., Yelizarov, I.   +2 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Evaluating evidence-based recruitment strategies for Alzheimer's disease and related dementias clinical trial research: A literature review. [PDF]

J Prev Alzheimers Dis
Jacobson M, Deuschle C, Peneva D, Wang AN, Roache C, Walsh M, Ferrell PB, Manetas MA, Raman R, Aisen P, Goldman D.   +10 more
europepmc   +1 more source

DTEK – Development Strategy 2030 [PDF]

, 2014
Astafiev, Denys, Isakova, M.L., Pokusa, Yulia, Sai, K.S., Shapovalov, Yakiv, Астаф'єв, Денис, Покуса, Юлія, Сай, Катерина Сергіївна, Шаповалов, Яків, Ісакова, М.Л.   +9 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The retained-bridge traction strategy: a novel solution for secure defect closure following duodenal endoscopic full-thickness resection. [PDF]

Endoscopy
Zhang K, Hu S, Zhang X, Min M, Liu Y.
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Real-World Impact of a Simplified 'Test and Treat' Strategy for In-Hospital HCV Micro-Elimination. [PDF]

J Viral Hepat
You C, Diao Y, Tang J, Tang J, Deng W, Zheng C, Liao D, Song D, Wang J, Pu Y.   +9 more
europepmc   +1 more source