Results 181 to 190 of about 4,606,527 (317)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Evolving top-down approaches for single-atom catalysis: synthesis and specialized applications. [PDF]

Chem Sci
Tian L, Wu Y.
europepmc   +1 more source

The Development of Coping Strategies: Main Approaches

, 2021
M. Yu. Kuzmin, Л. В. Сутурина
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Optimizing Workflow for OncotypeDX Result Turnaround Time at a Safety Net Hospital. [PDF]

Glob J Qual Saf Healthc
Wu J, Hung C, Sin HG, Bell T, Friedman EB, Li A, O'Leary XL, Shukla PS.   +7 more
europepmc   +1 more source

Implementation Strategy Research on Team Graduation Design of Automobile Specialties Based on Engineering Project [PDF]

, 2015
Peijiang Chen
openalex   +1 more source

STRATEGY ANALYSIS OF BUILDING CUSTOMER LOYALTY INDIHOME PT. TELECOMMUNIKASI INDONESIA Tbk

, 2023
Dhery Wiranata Surya, Endang Sulistya Rini, Beby Karina Fawzeea Sembiring   +2 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Systematic variation in proportion judgments: Spatial features impact adults' strategies and decisions. [PDF]

J Exp Psychol Gen
Hurst MA, Levine SC.
europepmc   +1 more source

Improving Reading Comprehension Through Directed Reading Thinking Activity (DRTA) Strategy For The Eight Grade Students of SMP Negeri 17 Medan In The Academic Year Of 2016-2017 [PDF]

, 2017
Leli Sari
openalex