Results 241 to 250 of about 11,624,639 (349)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Optimization of dynamic incentive strategies for public transportation based on reinforcement learning and network synergy effect. [PDF]

Sci Rep
Chen Y, Wang S.
europepmc   +1 more source

Market Development Strategies for Florida Fresh Sweet Corn: Findings from a Consumer Survey, 2001

, 1969
Tom Stevens, Robert L. Degner, Kimberly L. Morgan, Chris DeBodisco, Lisa House   +4 more
openalex   +2 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Effect of emotion on hawk-dove game for two players with different strength. [PDF]

Sci Rep
Gao Y, Long H, Wang Z, Chen R.
europepmc   +1 more source

The Survival Strategies of a Complex Western-Type Educational-Religious Organization in an Eastern Culture: a Case-Study of the Hong Kong Baptist College.

, 1969
Mark Anderson
openalex   +2 more sources

Creating strategy by design [PDF]

, 2009
Carlopio, James R.
core  

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

AI enhanced diagnostic accuracy and workload reduction in hepatocellular carcinoma screening. [PDF]

NPJ Digit Med
Lu RF, She CY, He DN, Cheng MQ, Wang Y, Huang H, Lin YD, Lv JY, Qin S, Liu ZZ, Lu ZR, Ke WP, Li CQ, Xiao H, Xu ZF, Liu GJ, Yang H, Ren J, Wang HB, Lu MD, Huang QH, Chen LD, Wang W, Kuang M.   +23 more
europepmc   +1 more source