Results 51 to 60 of about 4,207,100 (284)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Passenger Experience Management Strategies for Bangkok Suvarnabhumi Airport

open access: yesTourism and Hospitality
Despite growing global interest in customer experience management, limited research has systematically integrated both quantitative and qualitative approaches to identify service performance gaps and formulate strategic responses in airport settings ...
Supanat Wattanakamolchai   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Aligning Research Plans with Research Strategy [PDF]

open access: yesمطالعات مدیریت راهبردی, 2018
Nowadays, the main concern of most organizations is the formulation and implementation of the strategies that ensure their success and their survival in a varying and complex environmental condition, on the other hand, many strategies fail in ...
Nasser Shahsavari Pour   +2 more
doaj  

Development of Strategic Plan (Formulation, Implementation and Evaluation) of Physical Education in Lorestan Province by SWOT Approach [PDF]

open access: yesپژوهش در نظام‌های آموزشی, 2020
The purpose of this study was to develop a strategic plan (formulation, implementation and evaluation) of physical education in Lorestan province. The study was descriptive and applied and the statistical population of the study consisted of 500 people ...
ahmadreza azizi   +2 more
doaj  

Filters in the Strategy Formulation Process

open access: yesJ. Univers. Comput. Sci., 2003
JUCS - Journal of Universal Computer Science Volume Nr.
Ilmola,Leena, Kotsalo-Mustonen,Anna
openaire   +1 more source

E-commerce strategy formulation [PDF]

open access: yes, 2005
Many large organisations find it difficult to develop an e-commerce strategy. Senior management should first develop a comprehensive understanding of what it means to become e-commerce enabled before deciding whether or not to pursue that route. With e-commerce comes major changes that must be carefully planned and coordinated to avoid chaos and ...
Les Labuschagne, Jan H. P. Eloff
openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Business Strategy of CV Jaya Sampurna in Facing Soft Drink Distributor Competition in Bekasi

open access: yesBinus Business Review, 2015
CV Jaya Sampurna is a soft drink distributor in Bekasi. Distributor company has a low profit margin, moreover the product sold is Fast Moving Consumers Goods with a very low profit margin (3.5%–5%). Therefore the company depends on a high volume of sales.
Seri Nurmala, Hartiwi Hartiwi
doaj   +1 more source

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