Results 71 to 80 of about 1,259,445 (289)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Stable Prehensile Pushing: In-Hand Manipulation with Alternating Sticking Contacts

open access: yes, 2018
This paper presents an approach to in-hand manipulation planning that exploits the mechanics of alternating sticking contact. Particularly, we consider the problem of manipulating a grasped object using external pushes for which the pusher sticks to the ...
Chavan-Dafle, Nikhil, Rodriguez, Alberto
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Filters in the Strategy Formulation Process

open access: yesJ. Univers. Comput. Sci., 2003
JUCS - Journal of Universal Computer Science Volume Nr.
Ilmola,Leena, Kotsalo-Mustonen,Anna
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Information system strategy formulation: Some key issues

open access: yesSouth African Journal of Business Management, 1984
Expert observers are predicting more turbulent times for the 1980's. This is having a major impact on the way senior management is approaching its task, which grows more difficult every year.
N. Duffy
doaj   +1 more source

How to transfer discontinuous technology into radical innovation: Some evidence from three nanotech cases [PDF]

open access: yes
In this paper the focus is on the strategy formulation processes, specifically supportive methods and structures, which address various managerial issues concerning discontinuous technologies and radical innovation in the early phase of strategic ...
Herstatt, Cornelius   +2 more
core  

An Adaptive Mechanism for Accurate Query Answering under Differential Privacy

open access: yes, 2012
We propose a novel mechanism for answering sets of count- ing queries under differential privacy. Given a workload of counting queries, the mechanism automatically selects a different set of "strategy" queries to answer privately, using those answers to ...
Li, Chao, Miklau, Gerome
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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