Results 71 to 80 of about 3,218,936 (303)
Almost-dominant Strategy Implementation [PDF]
Though some economic environments provide allocation rules that are implementable in dominant strategies (strategy-proof), a significant number of environments yield impossibility results.
James Schummer
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Dominant Strategy Implementation in Economic Environments [PDF]
We study dominant strategy implementation especially in economic environments. We first show that in general environments, strategy-proofness and quasi-strong-non-bossiness together are necessary and sufficient for dominant strategy implementation via ...
Hideki Mizukami, Takuma Wakayama
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Aligning Research Plans with Research Strategy [PDF]
مطالعات مدیریت راهبردی, 2018 Nowadays, the main concern of most organizations is the formulation and implementation of the strategies that ensure their success and their survival in a varying and complex environmental condition, on the other hand, many strategies fail in ...
Nasser Shahsavari Pour +2 more
doaj
Bayesian and Dominant Strategy Implementation Revisited [PDF]
We consider a standard social choice environment with linear utility and one-dimensional types. We show by counterexample that, when there are at least three physical alternatives, Bayes-Nash Incentive Compatibility (BIC) and Dominant Strategy Incentive ...
Alex Gershkov +2 more
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Obstacles Finding Pattern for Bank's Strategic Marketing [PDF]
مطالعات مدیریت راهبردی, 2016 Research on the implementation of marketing plans does not in line with marketing formulation and despite design qualitative and quantitative tools and comprehensive model to strategy formulation, a few number of research activities have been considering
Asghar Moshabaki, Nina Pourebrahimi
doaj
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source