Results 81 to 90 of about 7,512,964 (290)

The challenges of implementing strategy

open access: yes, 2018
Strategy implementation is a hot topic today. Managers spend billions of dollars on consulting and training in the hope to create brilliant strategies. But all too often brilliant strategies do not translate into brilliant performance.
Verweire, Kurt
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Progress report on implementation aspects of the Thames River Basin water management study [PDF]

open access: yes, 1978
This progress report identifies the preliminary stance adopted by the Thames River Implementation Committee towards the 29 recommendations contained in the 1975 Thames River Basin Water Management Study and outlines the activities carried out by the ...
Thames River Implementation Committee
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Bioenergy Strategy 2020-2027

open access: yes, 2020
This strategy is founded on intelligence from global and regional trends in bioenergy production and consumption and an understanding of the local bioenergy industry status.

core  

The Future of Research in Strategy Implementation in the BRICS Context

open access: yesBBR: Brazilian Business Review, 2017
Albeit the development of the capacity to implement strategic change being a challenge to modern organizations, the studies in this area have prioritized intern issues of the organization, relegating it as a secondary plan, the contextual factors ...
Geovana Alves de Lima Fedato   +2 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Implementation of the concept of green logistics reffering to it applications for road freight transport enterprises

open access: yesBusiness: Theory and Practice, 2013
The article examines a scientific and practical problem concerning the ability to implement a concept of green logistics with reference to IT applications for Lithuanian road freight transport enterprises.
Aidas Vasilis Vasiliauskas   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Factors influencing top management team dynamics for successful strategy implementation

open access: yesSouth African Journal of Business Management
Purpose: This study explores the factors influencing top management team (TMT) dynamics to successfully implement an organisation’s strategy. It seeks to understand how such factors influence the TMT’s decision-making regarding strategy implementation ...
Yoliswa S. Mvubu   +2 more
doaj   +1 more source

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