Results 61 to 70 of about 1,224,997 (273)

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

Stratification and summer protist communities in the Arctic influenced coastal systems of Nunavik (Québec, Canada)

Frontiers in Marine Science
Phytoplankton and other protists in the 3 µm to 50 µm size fraction are grazed on by zooplankton and form the base of Arctic marine food webs essential for local indigenous communities.
Loïc Jacquemot, Loïc Jacquemot, Jean-Éric Tremblay, Carlee Morency, Carlee Morency, Connie Lovejoy, Connie Lovejoy   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Effects of Admission Policies on Rates of Family Migration in European States, 2008–2019

Nordic Journal of Migration Research
This study investigates whether and how much family migration policies have influenced patterns of family migration in European states. Family migration has been the largest category of entry in many Western countries in recent decades, and it has been ...
Anton Ahlén
doaj   +1 more source

Search for vertical stratification of metals in atmospheres of blue horizontal-branch stars [PDF]

, 2007
The observed abundance peculiarities of many chemical species relative to the expected cluster metallicity in blue horizontal-branch (BHB) stars presumably appear as a result of atomic diffusion in the photosphere. The slow rotation (typically $v\sin{i}$
B. B. Behr, Behr, Behr, Behr, Behr, Behr, Bonifacio, D. Bohlender, F. LeBlanc, Fabbian, Ferraro, G. A. Wade, Glaspey, Grundahl, Grundahl, Hauschildt, Hui-Bon-Hoa, Khalack, Khalack, Khan, Kupka, Landstreet, Landstreet, Michaud, Moehler, Moehler, Moehler, Moehler, Moehler, Pace, Peterson, Pickering, Raassen, Recio-Blanco, Sandage, V. R. Khalack, Wade   +36 more
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Stratification Trees for Adaptive Randomization in Randomized Controlled Trials

, 2020
This paper proposes an adaptive randomization procedure for two-stage randomized controlled trials. The method uses data from a first-wave experiment in order to determine how to stratify in a second wave of the experiment, where the objective is to ...
Tabord-Meehan, Max
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

How good are we at determining risk? Quantifying the accuracy of clinician determined risk for VTE prophylaxis [PDF]

, 2017
Objectives: Create and validate a simple tool for concurrent audits of risk stratification, compliance and documentation Evaluate accuracy of clinician risk stratification and prophylatic ordering practice compared with a standardized Caprini RAM across
Bauer, Tyler M., Beck, Johanna, Cowan, MD, Scott W., Dukleska, MD, Katerina, Dworkin, Myles, Johnson, MD, MPH, Adam P., Merli, MD, Geno J., Patel, RN, Kamini D.   +7 more
core   +1 more source