Results 271 to 280 of about 1,337,955 (380)

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Effect of Temperature and Covering Structures in Seed Dormancy and Germination Traits of Manchurian Striped Maple (<i>Acer tegmentosum</i> Maxim.) Native to Northeast Asia. [PDF]

Plants (Basel)
Kim S, Ko CH, Kwon HC, Rhie YH, Lee SY.
europepmc   +1 more source

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

The TgWRKY24 transcription factor is involved in releasing seed dormancy by responding to abscisic acid signals in Tulipa thianschanica. [PDF]

BMC Plant Biol
Sun Z, Ji Y, Liu S, Yan Y, Zheng Y, Xue L, Lei J, Zhao J.   +7 more
europepmc   +1 more source

Embryo development in seeds of Ilex paraguariensis A.St.-Hil. in stratification treatments

Rosani Klein Reinke, Mara Cíntia Winhelmann, Léo Jaime de Vargas, Júlia Gastmann, Elisete Maria de Freitas, Claudimar Sidnei Fior, Shirley Martins Silva   +6 more
openalex   +2 more sources

Cold stratification complements cold water in enhancing the germination of Juniperus procera seeds

, 2017
Debissa Lemessa, Debissa Lemessa, Hailu Negussie, Seid Melesse, Motuma Didita   +4 more
openalex   +2 more sources

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source

Allelic variations in GA20ox3 regulate fruit length and seed germination timing for high-altitude adaptation in Arabidopsis thaliana. [PDF]

Nat Commun
Gao X, Lou S, Han Y, Zheng Y, Feng X, Zhang H, Liu X, Hou J, Yao Y, Song Y, Liu M, Gu S, Liang R, Tan L, Feng L, Mei D, Jiang X, Sun P, Liu H, Jiang Y, Liu J.   +20 more
europepmc   +1 more source

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu, Liyuan Gao, Liyang Wang, Xueke Wang, Lin Jia, Mengyan Deng, Liming Tang, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao   +10 more
wiley   +1 more source

Protocol for efficient germination of Castilleja (Orobanchaceae) for chemical haustorium induction and parasite-host interaction studies. [PDF]

STAR Protoc
Bashyal S, Müller LM, Chory J, Bürger M.   +3 more
europepmc   +1 more source