Results 281 to 290 of about 1,337,955 (380)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Analysis of the Factors Affecting Germination of <i>Cnidium monnieri</i> Seeds and Its Endogenous Inhibitory Substances. [PDF]

Plants (Basel)
Wei Q, Shan S, Zhao S, Liu C, Ge F, Cui H, Chen F.   +6 more
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Deer impact seedbanks and plant communities over 18 years of post-agricultural succession. [PDF]

PLoS One
Westbrook AS, Butler-Jones A, Morris SH, Goldman M, Agrawal A, DiTommaso A.   +5 more
europepmc   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Impact of cryopreservation on DNA damage in Acer platanoides L. seeds evaluated by the comet assay. [PDF]

Sci Rep
Plitta-Michalak BP, Ramos AA, Trusiak M, Ratajczak E, Michalak M.   +4 more
europepmc   +1 more source

Modern and Ancient Genomes Reveal Neolithic Paternal Expansions of Millet and Rice Farmers and Demic Diffusion from China into Mainland Southeast Asia

Advanced Science, EarlyView.
This study clarifies the genetic patterns of paternal lineages across East Asia and Mainland Southeast Asia. Han populations are relatively homogeneous, whereas southern ethnolinguistic minorities display regional structures. Shared Y‐chromosome lineages indicate Neolithic expansions and extensive north‐south gene flow, supporting demic diffusion ...
Yunhui Liu, Lintao Luo, Yutong Jiang, Minzhu Zhao, Ting Yang, Zhiyong Wang, Lisiteng Luo, Yuhang Feng, Zihao Zhu, Yuzhu Wang, Limei Zhang, Bofeng Zhu, Chao Liu, Renkuan Tang, Mengge Wang, Guanglin He   +15 more
wiley   +1 more source

DNA Double Strand Break Repair Is Important for the Longevity of Primed Seeds. [PDF]

Plant Cell Environ
Waterworth WM, Wang D, Dsilva LS, West CE.   +3 more
europepmc   +1 more source

[Effect of seed stratification in three seed species of the genus Pinus [germination]]. [Spanish]

, 1979
Y Villagomez Aguilar, Carrera Garcia
openalex   +1 more source

Yield of quinoa (Chenopōdium quīnoa Willd.) under the effect of cold stratification of seeds

Svitlana Kalenska, N. V. Novytska, O. M. Martynov, Vadym Melnychenko, O. P. Chubko, D. S. Yelizarov   +5 more
openalex   +2 more sources