Results 111 to 120 of about 532,019 (236)

Ophthalmic characteristics of the study sample, stratified by recommendation for ophthalmic care (N = 1,226).

, 2018
Ophthalmic characteristics of the study sample, stratified by recommendation for ophthalmic care (N = 1,226).
Jochem König (51965), Martina F. Schmidt (5018858), Michael S. Urschitz (5018852), Heike M. Elflein (6037913), Christiane Diefenbach (5018849), Kathleen Schnick-Vollmer (5018855), Alexander K. Schuster (841118), Christine Gräf (5018861)   +7 more
core   +1 more source

SupportPrim-a computerized clinical decision support system for stratified care for patients with musculoskeletal pain complaints in general practice: study protocol for a randomized controlled trial. [PDF]

Trials, 2023
Lervik LCN, Vasseljen O, Austad B, Bach K, Bones AF, Granviken F, Hill JC, Jørgensen P, Øien T, Veites PM, Van der Windt DA, Meisingset I.   +11 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Translation and Adaptation of the French Version of the Risk Stratification Index, a Tool for Stratified Care in Chronic Low Back Pain: A Pilot Study. [PDF]

Medicina (Kaunas), 2022
Naïr A, Lin CI, Wippert PM.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Estimated adherence to PMTCT care during four months immediately preceding delivery stratified by model.

, 2018
Estimated adherence to PMTCT care during four months immediately preceding delivery stratified by model.
Mhairi Maskew (138509), Constance Mongwenyana (361724), Cynthia Nyoni (2736340), Ian Sanne (170641), Sydney Rosen (213204), Dorah Mokaba (5702915), Given Mohomi (5702912), Matthew P. Fox (213205), Lise Jamieson (3705994), Lawrence Long (320846)   +9 more
core   +1 more source

Feasibility of delivering and evaluating stratified care integrated with telehealth ('Rapid Stratified Telehealth') for patients with low back pain: protocol for a feasibility and pilot randomised controlled trial. [PDF]

BMJ Open, 2022
Zadro JR, Needs C, Foster NE, Martens D, Coombs DM, Machado GC, Adams C, Han CS, Maher CG.   +8 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

A stratified care model for low back pain: healthcare utilization in primary care

, 2019
1:00 PM3:00pm-5:00pmUndergraduateIntroduction The aim of this study was to compare healthcare utilization data between a clinical trial (CT) cohort, a quality improvement research (QIR) cohort, and a retrospective (RT) cohort of patients with low back ...
Pflaster, Kara M
core