Results 111 to 120 of about 261,494 (266)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Linear stability of a stratified shear flow slowly varying in time

open access: yes, 2000
The inviscid linear stability of an unsteady stratified shear flow slowly varying in time is investigated. Results show that due to unsteadiness disturbances growth starts at Richardson number even much lower than predicted by the steady ...
SUSIN, FRANCESCA MARIA   +2 more
core  

Tracer dynamics in two-layer density stratified estuarine flow

open access: yes, 2014
This paper considers tidal-driven particle motion in Tampa Bay, Florida, USA under fully stratified conditions with riverine inflow. The flow field is modelled by means of the two-layer shallow-water equations solved on an adaptive quadtree grid using a ...
Taylor, Paul   +2 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

An experimental study of stratified-dispersed flow in horizontal pipes

open access: yes, 2014
The tracer method has been adopted to study stratified–dispersed flow in a horizontal pipe, 80 mm in diameter and 50 m long, operating at 5 Bar with nitrogen–water mixtures.
ANDREUSSI, PAOLO   +3 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

An analytical investigation of the physical dimensions of natural convection flow on a vertical heated plate [PDF]

open access: yes, 2010
Analytical results of the boundary layer of natural convection air flow on a vertical heated plate are presented for both isothermal and constant heat flux plates.
Alzwayi, A.S., Paul, M.C.
core  

Stratified Two-Phase Flow in Annular Seals

open access: yes, 2019
The present study concerns the leakage predictions in pressure annular centered seals operating in a two-phase (gas–liquid) smooth stratified flow pattern.
Afferrante, Luciano   +3 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy