Results 151 to 160 of about 261,494 (266)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Experimental Investigation on Two-phase Flow Pattern of Hydrocarbon Refrigerants in Shell Side of Helically Baffled Shell and Tube Heat Exchanger

open access: yesZhileng xuebao
Two-phase flow pattern of hydrocarbon working fluids in the shell side of a helically baffled heat exchanger for liquefied natural gas determines the heat transfer performance of the heat exchanger.
杨果成, 丁国良, 陈杰
doaj  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Phase flow rate measurements of annular flows

open access: yes
In the international oil and gas industry multiphase annular flow in pipelines and wells is extremely important, but not well understood. This thesis reports the development of an efficient and cheap method for measuring the phase flow rates in two phase
Al-Yarubi, Qahtan
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Withdrawal of layered fluid through a line sink in a porous medium

open access: yes, 1996
The flow induced when fluid is withdrawn through a line sink from a layered fluid in a homogeneous, vertically confined porous medium is studied. A nonlinear integral equation is derived and solved numerically. For a given sink location, the shape of the
Hocking, G.C., Zhang, H.
core  

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