Results 161 to 170 of about 261,494 (266)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Waves in Turbulent Stably Stratified Shear Flow

open access: yes, 2002
Two approaches for the identification of internal gravity waves in sheared and unsheared homogeneous stratified turbulence are investigated. First, the phase angle between the vertical velocity and density fluctuations is considered.
Jacobitz, F. G.   +3 more
core  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

In-cylinder flow and combustion studies in an air-assisted direct injection gasoline engine

open access: yes, 2004
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In-cylinder flows and CAI combustion were investigated in a single cylinder, air-assisted gasoline direct injection engine.
Leach, Ben Thomas
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

A note on withdrawal through a point sink in fluid of finite depth

open access: yes, 1996
Withdrawal flow through a point sink on the bottom of a fluid of finite depth is considered. The fluid is at rest at infinity, and a stagnation point is present at the free surface, directly above the point sink. Numerical solutions are computed by means
Hocking, Graeme C.   +5 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Short-wave vortex instabilities in stratified flow

open access: yes, 2013
Density stratification is one of the essential underlying physical mechanisms for atmospheric and oceanic flow. As a first step to investigating the mechanisms of stratified turbulence, linear stability plays a critical role in determining under what ...
Bovard, Luke
core  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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