Results 51 to 60 of about 397,778 (284)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A Web Platform Development to Perform Thematic Accuracy Assessment of Sugarcane Mapping in South-Central Brazil

open access: yesRemote Sensing, 2012
The ability to monitor sugarcane expansion in Brazil, the world’s largest producer and exporter of sugar and second largest producer of ethanol, is important due to its agricultural, economic, strategic and environmental relevance.
Arley Ferreira de Souza   +4 more
doaj   +1 more source

ACCURACY COMPARISON OF SIMPLE, SYSTEMATIC, AND STRATIFIED RANDOM SAMPLING FOR ESTIMATING POPULATION (MINIMARKET CASE IN INDONESIA) [PDF]

open access: yes, 2015
This paper aims to compare the accuracy of three methods of sampling, namely Simple Random Sampling (SRS), Systematic Random Sampling and Stratified Random Sampling. The data used as the simulation is data PODES 2011.
Abadi Wibowo, .   +3 more
core  

Quality of Medical Information Determine the Quality of Diagnosis Code [PDF]

open access: yes, 2019
The accuracy of the diagnosis code has implications for future patient care planning, provision of health services and patient care costs. Therefore, this study has analyzed the influence of the quality of medical information on the quality of the ...
Ismayani, A. (Ani)   +2 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A generalized exponential-type estimator for population mean using auxiliary attributes.

open access: yesPLoS ONE, 2021
In this paper, we propose a generalized class of exponential type estimators for estimating the finite population mean using two auxiliary attributes under simple random sampling and stratified random sampling.
Sohail Ahmad   +3 more
doaj   +1 more source

Fitting Proportional Odds Models to Educational Data with Complex Sampling Designs in Ordinal Logistic Regression [PDF]

open access: yes, 2013
The conventional proportional odds (PO) model assumes that data are collected using simple random sampling by which each sampling unit has the equal probability of being selected from a population.
Koirala, Hari, Liu, Xing
core   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Training Set Construction for Genomic Prediction in Auto-Tetraploids: An Example in Potato

open access: yesFrontiers in Plant Science, 2021
Training set construction is an important prerequisite to Genomic Prediction (GP), and while this has been studied in diploids, polyploids have not received the same attention.
Stefan Wilson   +5 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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