Results 51 to 60 of about 150,322 (251)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Progress in Fishery SciencesBiodiversity assessment in fisheries plays a crucial role in conserving marine ecosystem diversity. Accurate survey data serve as the foundation for ensuring the precision of quantitative analysis and the effectiveness of resource conservation measures ...
Yuexiu DENG +5 more
doaj +1 more source
Remotely sensed data controlled forest inventory concept
European Journal of Remote Sensing, 2018 Nowadays, the image of the forest in Germany is changing from monoculture areas to very mixed forests, where individual stands are no longer clearly visible.
Adelheid Wallner +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A new modified estimator of population variance in calibrated survey sampling
Scientific ReportsIn survey statistics, estimating and reducing population variation is crucial. These variations can occur in any sampling design, including stratified random sampling, where stratum weights may increase the variance of estimators. Calibration techniques,
Riffat Jabeen +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Observed and predicted first lactation milk yield in Surti buffaloes
Indian Journal of Animal Sciences, 2014 305FLMY was predicted from fortnightly, monthly and bimonthly test day milk yields using 2 sampling schemes (systematic and stratified random sampling) in Surti buffaloes maintained at Network Project on Surti buffaloes, Livestock Research Station ...
S P TAILOR, SHANKER SINGH
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Toward a principled sampling theory for quasi-orders
Frontiers in Psychology, 2016 Quasi-orders, that is, reflexive and transitive binary relations, have numerous applications. In educational theories, the dependencies of mastery among the problems of a test can be modeled by quasi-orders.
Ali Ünlü, Martin Schrepp
doaj +1 more source