Results 101 to 110 of about 2,755,892 (287)

Dynamic data-enabled stratified sampling for trial invitations with application in NHS-Galleri. [PDF]

Clin Trials, 2023
Brentnall AR, Mathews C, Beare S, Ching J, Sleeth M, Sasieni P.   +5 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A Level-Cascaded Framework for Multiscale Forest Aboveground Biomass Estimation Using UAV-LiDAR and Public Data

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Accurate assessment of forest aboveground biomass (AGB) and its density (AGBD) is critical for understanding carbon cycling and climate change in terrestrial ecosystems.
Liwei Yao, Qingyun Du, Wenli Huang, Xinlian Liang, Yang Hu, Mingke Li   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Efficient Evaluation of Prediction Rules in Semi-Supervised Settings under Stratified Sampling. [PDF]

J R Stat Soc Series B Stat Methodol, 2022
Gronsbell J, Liu M, Tian L, Cai T.
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Enhancing Bee Mite Detection with YOLO: The Role of Data Augmentation and Stratified Sampling

Agriculture
Beekeeping is facing a serious crisis due to climate change and diseases such as bee mites (Varroa destructor), which have led to declining populations, collapsing colonies, and reduced beekeeping productivity. Bee mites are small, reddish-brown in color,
Hong-Gu Lee, Jeong-Yong Shin, Su-Bae Kim, Min-Jee Kim, Moon S. Kim, Hoyoung Lee, Changyeun Mo   +6 more
doaj   +1 more source

The validation of the Norwegian Basic Psychological Need Satisfaction and Frustration Scale: A stratified sampling procedure. [PDF]

Front Psychol, 2022
van der Kaap-Deeder J, Sanchez A, Johannessen MRA, Stenseng F, Saksvik-Lehouillier I, Heissel A.   +5 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Warfarin maintenance dose prediction for Chinese after heart valve replacement by a feedforward neural network with equal stratified sampling. [PDF]

Sci Rep, 2021
Ma W, Li H, Dong L, Zhou Q, Fu B, Hou JL, Wang J, Qin W, Chen J.   +8 more
europepmc   +1 more source