Results 121 to 130 of about 60,358 (297)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Stray dogs in urban fragments: relation between population’s perception of their presence and socio-demographic factors

open access: yesPesquisa Veterinária Brasileira
: Stray dogs are associated with environment and public health impacts. São Paulo is a city with approximately 2.5 million owned dogs and until the time of writing no studies describing the distribution of the stray dog population have been conducted in ...
Aline G.A. Guilloux   +5 more
doaj   +1 more source

Stray light control in an off-axis three-mirror anastigmat telescope

open access: yes
reservedStray light is a critical factor affecting the performance of optical payloads, particularly in off-axis three-mirror anastigmatic (TMA) telescopes, whose asymmetrical geometry makes the mitigation of scattered light particularly challenging ...
LUCCHINI, MIRIANA
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Optimal Design of Stray Inductance of Busbar in Two-level IGCT Power Module

open access: yesKongzhi Yu Xinxi Jishu, 2015
Stray inductance of busbar in converter will have serious influence on the turn-off characteristic of IGCTs, and it may increase voltage stress and turn-off losses of IGCTs, even destroy the device.
LIU Jianping   +3 more
doaj  

A Stray

open access: yesAmerican Journal of Psychiatry Residents' Journal, 2021
openaire   +1 more source

PENERAPAN MODEL PEMBELAJARAN KOOPERATIF TIPETWO STAY TWO STRAY PADA PELAJARAN GEOGRAFIDI KELAS VII SMP NEGERI 2 KUTA BARO KABUPATEN ACEH BESAR

open access: yes, 2013
Kata Kunci : Model Kooperatif Two Stay Two Stray, Prestasi BelajarPenciptaan suasana belajar yang menyenangkan akan mengaktifkan potensi dan meningkatkan daya pikir siswa.

core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

stray-line

open access: yes, 1973
stray-line nWhere gill nets were used, they were fastened to the land by a rope called a stray-line at the other end of the net, an anchor was dropped to prevent the net from drifting around.DNE-cit GMS Sept 73Used IUsed I1Used IPALE (OIL), straw ...

core  

Home - About - Disclaimer - Privacy