Results 141 to 150 of about 60,358 (297)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Tandem Reconnection and Cusp Electrodynamics Reconnaissance Satellites (TRACERS) Magnetic Control Plan. [PDF]

Space Sci Rev
Miles DM, Lasko A, Blandin M, Bounds S, Caron R, Carton A, Dolan J, Dvorsky R, Finley MG, Flores A, Goss C, Greene K, Halekas J, Hospodarsky GB, Kletzing CA, Mark D, Miller I, Nguyen P, Omar S, Orrill E, Prasad R, Rospos A, Slagle A, Strangeway RJ, Torbert R, Vernot R, Washington A.   +26 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Higher shock index at presentation is associated with mortality in stray cats at an emergency medical center. [PDF]

PeerJ
Kim C, Seo D, Lim S, Namgoong B, Lee N, Kim I, Heo S, Shin H, Kang JH, Park S, Park J, Kim H, Shin H, Kim MS.   +13 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Metagenomic Next-Generation Sequencing Analysis of Pathogens in Infected Wounds from Dog and Cat Bites - China, 2021-2025. [PDF]

China CDC Wkly
Huang L, Wang L, Wang X, Zhang X, Yu X, Yang J, Zhang W, Yang J, Ji W, Cao Y, Zheng Y, Gai W, Jiang M, Liang Y.   +13 more
europepmc   +1 more source

The Stray Bullet Project [PDF]

Academic Emergency Medicine, 2019
Maria, Abou Nader, Rana, Sharara-Chami
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Microscopic Leaching Mechanism of Fly Ash Geopolymer (FAG) Under Coupled Stray Current and Soft Water. [PDF]

Polymers (Basel)
Liu F, He Z, Tang R, Zheng X, Wang B, Wang X, Yuan X.   +6 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source