Results 111 to 120 of about 10,858,871 (318)

The effect of stray currents on reinforced concrete structures [PDF]

Diplomová práce se zabývá negativními vlivy bludných elektrických proudů na železobetonové konstrukce. Součástí práce je teoretická část s popsáním problematiky a možných řešení, dále také část s příklady řešení této problematiky v praxi.The thesis ...
Anna Krouská
core  

Correction of stray magnetic fields caused by cable currents is essential for human in-vivo brain magnetic resonance current density imaging (MRCDI) [PDF]

, 2019
Accurate mapping of current flows in the human brain is important for many neuroscientific applications. MRCDI is an emerging method, which combines MRI with externally applied alternating currents to derive current flow distributions based on ...
Scheffler, K., Hanson, L., Thielscher, Axel, Göksu, C., Hanson, Lars G., Scheffler, Klaus, Siebner, H., Thielscher, A., Siebner, Hartwig R., Göksu, Cihan   +9 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Stray current corrosion of copper sheathing and keel cooling pipe of a 36' trawler [PDF]

, 1968
The results of investigations into the cause of an accelerated corrosion of copper sheathing and keel cooling pipe of a 36' wooden trawler are reported.
Ravindran, K.
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Pipeline failure evaluation and prediction using failure probability and neural network based on measured data

Heliyon
The chemical corrosion of metals in large industries such as oil and gas is a fundamental and costly problem. Gas transmission and distribution pipes and the other structures submerged in the soil and in an electrolyte, according to the existing ...
H. Noroznia, M. Gandomkar, J. Nikoukar
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source