Results 51 to 60 of about 26,366,925 (292)

Principal-Component Calculation of Stray Light for Infrared Detection

, 2011
Analysis and calculation of stray light is important to improve the performance of infrared detection system. In this article, we mainly discussed two sources: earth and atmosphere emission and thermal stray radiation.
Heng Can Li, Jin Xing Niu
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Analysis and Experiment for Wireless Power Transfer Systems with Two Kinds Shielding Coils in EVs

Energies, 2020
Electric vehicles (EVs) with wireless power transfer (WPT) systems are convenient, but WPT technology will produce a strong stray electromagnetic field (EMF) in the surrounding space when the system works with high power. Shielding coils can reduce stray
Yushan Wang, Baowei Song, Zhaoyong Mao
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Research on Coherent Stray Light Fringes in Interference Compensation Testing

Photonics
Testing accuracy is an essential factor in determining the manufacturing accuracy of aspheric mirrors. Because of the complexity of the null compensation test, the coherent stray lights generated by multiple reflections and transmissions between optical ...
Yutong Sun, Qiang Cheng, Haixiang Hu, Xin Zhang, Xiaokun Wang, Longxiang Li, Donglin Xue, Xuejun Zhang   +7 more
doaj   +1 more source

Analysis of the influence of micrometeoroids on the stray light of the TianQin telescope

Optics Express
This study establishes a comprehensive evaluation methodology for micrometeoroid impact-induced stray light in the TianQin gravitational wave detection telescope. By integrating the Grün flux model with baffle design, and systematically analyzing crater morphology and contamination splattering parameters through damage equations ...
Xinxin Liu, Yiping Wang, Zizheng Li, Xin Zhang, Shanxiang Liang, Xuefeng Zhang, Wenbo Chang, Shanqing Ynag   +7 more
openaire   +2 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source