Results 91 to 100 of about 61,164 (293)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Loading of a cold atomic beam into a magnetic guide

, 2002
We demonstrate experimentally the continuous and pulsed loading of a slow and cold atomic beam into a magnetic guide. The slow beam is produced using a vapor loaded laser trap, which ensures two-dimensional magneto-optical trapping, as well as cooling by
Aclan, A., Cren, P., Dalibard, J., Guéry-Odelin, D., Roos, C. F.   +4 more
core   +2 more sources

Stray Losses in Transformers [PDF]

Transactions of the American Institute of Electrical Engineers, 1913
C. Fortescue, W. M. McConahey
openaire   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Echinococcosis/Hydatidosis in Ilam Province, Western Iran

Iranian Journal of Parasitology, 2013
Background: Hydatidosis is a zoonotic disease of global prevalence. It causes considerable health problems and economic losses throughout the world, including Iran.
Jahangir Abdi, Morovat Taherikalani, Kheirolah Asadolahi, Mohammad Emaneini   +3 more
doaj   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Penentuan Pembebanan Maksimum Transformator Daya Yang Menyuplai Personal Computer (PC)

Dinamika Rekayasa, 2009
Personal computer is electronic equiment that use solid state device, such as rectifiers, so it to be source of harmonic current. Harmonic current is sinusoidal current with multiple frequency of fundamental current which will be increase power losses ...
Hari Prasetijo, Hesti Susilawati
doaj  

Detection of Vacuum Birefringence with Intense Laser Pulses

, 2004
We propose a novel technique that promises hope of being the first to directly detect a polarization in the quantum electrodynamic (QED) vacuum. The technique is based upon the use of ultra-short pulses of light circulating in low dispersion optical ...
Aleksandrov, Andre N. Luiten, Askenazy, Bakalov, Becker, Black, Bondu, Bregant, Brunner, Burke, Cameron, Day, Diddams, Drever, Euler, Hall, Heisenberg, Heyl, Hils, Jesse C. Petersen, Jones, Jones, Jones, Lee, Ma, Petersen, Schwinger, Uehara, Walsh, Weisskopf, Wilson   +30 more
core   +1 more source

Stray Losses in Transformer Clamping Plate

, 2006
Stray losses in transformer clamping plate can be a considerable part of the overall stray loss in transformer. In this paper clamping plate loss distribution is shown. Methods of loss reduction were analyzed. Impact of changing clamping plate position and bracket design, material and position on the stray losses was analyzed.
Štih, Željko, Janić, Žarko, Valković, Zvonimir   +2 more
openaire   +1 more source