Results 161 to 170 of about 61,164 (293)

Approaching the physical limits of specific absorption rate for synthetic antiferromagnetic nanodisks in hyperthermia applications. [PDF]

Biomater Sci
Scheibler S, Wei H, Ackers J, Helbig S, Koraltan S, Peremadathil-Pradeep R, Krupinski M, Graeser M, Suess D, Herrmann IK, Hug HJ.   +10 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Co-infection of fasciolosis and hydatidosis in cattle at Jimma Municipal Abattoir, Ethiopia: Prevalence, risk factors, and economic impact. [PDF]

Parasitol Res
Dahesa GD, Kebede IA, Tilahun AA, Borena BM, Muleta YJ, Gebremeskel HF, Wadajo SR, Lemu GH, Gudina SB.   +8 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Flux Channeling Induced Nanoconfinement and Enhancement of Microwaves Imaged by Rabi Oscillation Mapping. [PDF]

Nano Lett
Rable J, Dwivedi J, Samarth N, Stevenson P, Bansil A, Kar S.   +5 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Prioritizing interventions for echinococcosis prevention in China: a population attributable fraction analysis. [PDF]

Lancet Reg Health West Pac
Xu S, Danzeng Q, Guo B, Xu P, Gu L, Zhao Y, Guo X, Tang Y, Chang Y, Wu G, Zhao X.   +10 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A time-space Bayesian regression model of rabies cases in the animal population of Kazakhstan (2013-2023). [PDF]

Front Vet Sci
Gomez-Buendia A, Yessembekova G, Kadyrov A, Mukhanbetkaliyev Y, Cerviño-Luridiana E, Alvarez J, Perez AM, Abdrakhmanov SK.   +7 more
europepmc   +1 more source