Results 111 to 120 of about 3,939,893 (294)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

One Kind of Green New Method for Detection of Inside Layer Cracks of Aircraft Multilayer Structures

Engineering Proceedings
To address the technical challenges in detecting internal cracks within aircraft metallic multilayer structures, we have employed the environmentally friendly detection technique of remote-field eddy current (RFEC).
Huabin Huang, Zhiwei Peng, Mao Xu
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Digital collaborative exploration and practice of ground vibration test for full-scale aircraft

Hangkong gongcheng jinzhan
The ground vibration test of full-scale aircraft has the characteristics of multiple coordination units, complex system, long implementation time and high risk.
BAI Chunyu, LIANG Sen, SONG Qiaozhi
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Measuring implementation strength: Literature review draft report 2012 [PDF]

, 2012
Measuring implementation strength (sometimes referred to as implementation intensity) is an important programme evaluation process which helps to understand why some programmes are successful and some fail, attribute outcomes to a programme, and ...
Schellenberg, JA, Bobrova, N, Avan, BI
core   +1 more source

The cumulative effects of strength and endurance training sessions on muscle force generation capacity over four days

, 2013
[Extract] The incorporation of strength and endurance training sessions in the one training program is known as concurrent training (CT) (11). Numerous studies have shown that CT induces sub-optimal strength adaptations (7, 10, 15).
Deakin, Glen, Doma, Kenji
core   +1 more source

Prediction of Random Crack Propagation Life of Thin Porous Plate with Multiple Site Damage

Engineering Proceedings
Based on the crack propagation rate test of LY12CZ aluminum alloy flat plate, the distribution characteristics of Paris formula parameters were characterized by the three-parameter logarithmic normal distribution, and a LY12CZ random crack propagation ...
Hanbin Sun, Xianmin Chen, Jun Yang
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source