Results 111 to 120 of about 7,757,408 (296)

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Dynamic Analysis of the Titanium Alloy Plate under Thermal-acoustic Loadings

open access: yesMATEC Web of Conferences, 2015
Hypersonic vehicles structures suffer complex combined loadings generally. For the thin-walled structures and thermal protection systems of the aircraft, high temperature and intensity acoustic loadings are the significant factors that leading to their ...
Zou Xuefeng, Guo Dingwen, Zhang Li
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Investigation on vibration fatigue crack growth behavior of notched cantilever beams

open access: yesHangkong gongcheng jinzhan
Aviation aircraft will be subjected to a large number of complex random vibration loads during service, and its structure is prone to vibration fatigue,which leads to damage or even failure,which can cause serious losses.
ZHANG Borui   +4 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

An updated review of nanotechnologies for the space elevator tether

open access: yes, 2010
The space elevator tether requires an extraordinary specific ultimate strength (ratio between ultimate strength and density) and carbon nanotubes (CNTs) have been identified as the ideal candidate because of their astonishing strength. This paper reviews
Brambilla, G.
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Thermal treatment and mechanical properties of aluminum-2021 [PDF]

open access: yes, 1970
Mechanical properties, after thermal treatments, are summarized for sheet and plate of copper-rich, high-strength, heat-treatable aluminum-2021. The alloy is quench sensitive, quench rate and variations in aging affect corrosion behavior.
Brennecke, M. W.
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Trade Union Strength [PDF]

open access: yes
Spanish trade unions enjoy an uncomfortable mix of high coverage and very low membership base. This state of affairs has arisen primarily because of state support for the collective representation system.
G Nombela, S Milner
core  

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