Results 91 to 100 of about 2,154,717 (261)

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Fatigue performance control strategy of TC11 and TC17 linear friction welded joints via annealing treatment

Frontiers in Materials
A post-weld annealing strategy was developed to control the high-cycle fatigue performance of dissimilar TC11/TC17 titanium alloy linear friction welded joints. By systematically varying the stress relief annealing temperature (590, 605, 630, and 650 °C),
Zishi Shen, Zishi Shen, Jun Yang, Jun Yang, Xianmin Chen, Xianmin Chen   +5 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

A prediction method for hydrodynamic load of seaplane with flow separation considered

Xibei Gongye Daxue Xuebao
During the early design phase of a seaplane, it is necessary to estimate the hydrodynamic load acting on the bottom structure of its fuselage. The flow separation is one of the important factors that makes it difficult to accurately analyse water load ...
REN Xuanqi, XU Fei, NIE Xiaohua, CHANG Liang, YANG Yang   +4 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Daily Supplementation of High Doses of Tocotrienol-Rich Fraction From Palm Oil Produced No Toxic Effects in Healthy Mice

Journal of Toxicology
The vitamin E derived from palm oil, known as the tocotrienol-rich fraction (TRF), has been reported to possess potent anticancer and immunomodulatory effects in numerous cell-based and animal models of breast cancer (BC). However, only a low dose of TRF
Nevvin Raaj Morgan, Saatheeyavaane Bhuvanendran, Purushotham Krishnappa, Ammu Kutty Radhakrishnan   +3 more
doaj   +1 more source

Aeroacoustic test system design and experimental research for counter-rotating propeller

Hangkong gongcheng jinzhan
The aerodynamic noise test of counter-rotating propellers in wind tunnels has the problems of difficult time coordination and high cost. The aerodynamic noise test system of counter-rotating propellers，which is capable of simulating the driving state of ...
CAO Qi, WEI Kai, NIE Yanping, YAN Qun, CHEN Yonghui   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Strength to strength [PDF]

Nature, 1993
openaire   +1 more source