Results 71 to 80 of about 2,154,717 (261)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Facta Universitatis. Series: Mechanical Engineering, 2016 Numerical simulation is performed to investigate the mesoscale stress-strain localization in a surface-modified commercial titanium alloy. The calculated crystalline microstructure corresponds to that observed in experiments and is accounted for in an ...
Ruslan Balokhonov +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Study on the Dynamic Mechanical Behavior of 2D C/SiC Composites at Medium Strain Rates
AerospaceTwo-dimensional C/SiC are promising candidates for use in high-temperature structures in aeroengines and thermal protection systems in the aerospace industry, which will be subjected to loads in various directions during service.
Xinyue Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
One Kind of Green New Method for Detection of Inside Layer Cracks of Aircraft Multilayer Structures
Engineering ProceedingsTo address the technical challenges in detecting internal cracks within aircraft metallic multilayer structures, we have employed the environmentally friendly detection technique of remote-field eddy current (RFEC).
Huabin Huang, Zhiwei Peng, Mao Xu
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Digital collaborative exploration and practice of ground vibration test for full-scale aircraft
Hangkong gongcheng jinzhanThe ground vibration test of full-scale aircraft has the characteristics of multiple coordination units, complex system, long implementation time and high risk.
BAI Chunyu, LIANG Sen, SONG Qiaozhi
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source