Results 101 to 110 of about 11,909,259 (293)

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Relationships of sun-protection habit strength with sunscreen use during outdoor sport and physical activity [PDF]

, 2012
The objective of this cross-sectional questionnaire study was to assess associations of a self-report index of sun protection habit strength with sunscreen use in sporting environments and outdoor physical activity. Participants (n = 234) in field hockey,
Gallois, C, Evie Leslie, Eakin, E, O'Riordan, D, Spathonis, K, Leslie, Evie, Elizabeth Eakin, Eakin, Elizabeth, Leslie, E, Owen, N, Lawler, Sheleigh, Spathonis, Kym, Lawler, S, Cindy Gallois, Berndt, N, McDermott, Liane, McDermott, L, David O’Riordan, O'Riordan, David, Owen, Neville, Sheleigh Lawler, Kym Spathonis, Liane McDermott, Nadine Berndt, Neville Owen, Gallois, Cindy, Berndt, Nadine   +26 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

THE RELATIONSHIP BETWEEN HANDGRIP STRENGTH AND PHYSICAL ACTIVITY BARRIERS IN PATIENTS WITH CHRONIC KIDNEY DISEASE UNDERGOING HEMODIALYSIS [PDF]

Purpose: The aim of this study is to investigate the relationship between handgrip strength (HGS) and physical activity barriers in patients with chronic kidney disease (CKD) undergoing hemodialysis.
Mehmet Ercan ODABAŞIOĞLU, Tahir DEDEOĞLU, Uğur DOĞAN   +2 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Development of an International Qualification Framework for the strength and conditioning profession: International Universities Strength and Conditioning Association Position Statement.

In the profession of strength and conditioning (S&C), there is a need for a standardised, comprehensive framework that can allow for the alignment of international certifications, qualifications, and standards.
Bird, Stephen P., Langford, Andrew, Flannagan, Aden, Marchetti, Paulo H.   +3 more
core   +1 more source

Characterization of physical activity levels in female breast cancer survivors : relationship with Lymphedema (AtiLinf) [PDF]

The development of lymphedema (LE) is a major concern in breast cancer treatment, and it is crucial to understand the best ways to prevent and treat it. Physical activity has shown to be effective, safe, and feasible in controlling complications arising ...
Tomás, María Teresa, Lobo, Pablo, Ralheta Duarte, Alice, Martinho Neto, Carla, Prates, Leonor, Neto, Carla Martinho, Duarte, Alice Ralheta   +6 more
core   +1 more source

Crohn's disease activity index and Vienna classification - Is it worthwhile to calculate before surgery? [PDF]

, 2006
Background: Crohn's disease (CD) patients with increased disease activity may reveal an increased risk for perioperative complications. The `Crohn's disease activity index' (CDAI) and the `Vienna classification' (VC) were developed for standardized ...
Jauch, Karl-Walter, Rentsch, M., Schlitt, H. J., Schlitt, H.J., Jauch, K.W., Beham, A.   +5 more
core   +1 more source