Results 81 to 90 of about 11,909,259 (293)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Effects Of Combined Strength And Endurance Training On Physical Performance And Biomarkers Of Healthy Young Women

, 2018
Kyröläinen, H, Hackney, AC, Salminen, R, Repola, J, Häkkinen, K, and Haimi, J. Effects of combined strength and endurance training on physical performance and biomarkers of healthy young women.
Repola, Johanna, Jari Haimi, Hackney, Anthony C., Kyröläinen, Heikki, Johanna Repola, Keijo Häkkinen, Salminen, Riikka, Häkkinen, Keijo, Anthony C. Hackney, Riikka Salminen, Haimi, Jari, Heikki Kyröläinen   +11 more
core   +1 more source

Preparation of Silicomanganese Slag-based Cementitious Materials and its Hydration Mechanism

Kuangchan zonghe liyong
[Objective] To explore the feasibility, mechanical properties and hydration mechanism of preparing cementitious materials by compounding silicon-manganese slag micro-powder with ordinary Portland cement and admixtures, and improve the comprehensive ...
Zhenwei SHEN, Mingyang LI, Hao ZHANG, Weike MA, Daoqing HU, Leqi SI   +5 more
doaj   +1 more source

Physical fitness of elderly persons with systemic arterial hypertension users of academies of the third age of Maringá-pr

Revista da Educação Física, 2020
This study investigated the physical fitness of elderly hypertensive users of the fitness zones  of the city of Maringá-PR. The subjects were 79 male and female elderly users of 13 fitness zones located in the city of Maringá-PR, with a diagnosis of ...
Daniel Vicentini de Oliveira, Leonardo Lopes Giacomin, Mateus Dias Antunes, Carla Thamires Laranjeira Granja, Eliakim Cerqueira da Silva, Kácia Valéria Miranda Oliveira Nascimento, José Roberto Andrade do Nascimento Júnior   +6 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

A comparative study of handgrip strength among sedentary and non-sedentary workers

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: India is a developing country with a rapid transformation in lifestyle including inappropriate diet and inadequate physical activity. More the physical activity greater will be the muscle strength.
Ahrsia Valavoor Fathima, Aswini R Dutt, Shankar K Bhat, Bhima Bhat, Ahris Valavoor Fakruddin   +4 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Activity-induced Regulation of Synaptic Strength through the Chromatin Reader, L3mbtl1. Mao et al.

, 2018
L3mbtl1 is an activity dependent chromatin reader protein that regulates homeostatic down-scaling. •Ctnnb1 is one of the target genes of L3mbtl1 that mediates synaptic homeostasis.
Kensuke Futai (255024)
core   +1 more source