Results 111 to 120 of about 5,501,103 (350)

An analysis of the fluctuations of the geomagnetic dipole

open access: yes, 2007
The time evolution of the strength of the Earth's virtual axial dipole moment (VADM) is analyzed by relating it to the Fokker-Planck equation, which describes a random walk with VADM-dependent drift and diffusion coefficients.
Bouligand   +16 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Static Strength Analysis and Optimization of the Roller Cone Bit Bearing Structure

open access: yesShiyou jixie, 2015
The tricone bit is prone to having a failure bearing under high WOB and high RPM.To improve the roller cone bit bearing structure stress,increase the tooth placement space and the thickness of the shell,a three dimensional model has been established ...
Li Bin   +3 more
doaj  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

ANALYSIS OF THE CONSTRUCTION OF THE CAR TRAILER FRAME IN TERMS OF CHANGING THE ASSEMBLY TECHNOLOGY

open access: yesScientific Journal of Silesian University of Technology. Series Transport
Car trailers are quite a popular means of transport and are offered in many versions, from single axle light trailers with a maximum permissible weight of 750 kg, through two- or more-axle specialized trailers.
Jacek CABAN   +4 more
doaj   +1 more source

Local and non-local normalised equivalent strain functionals for cyclic fatigue [PDF]

open access: yes, 2004
The concept of Cyclic Normalised Equivalent Strain Functionals (CNESnFs) suitable for lowcyclic fatigue is developed in this paper. It reduces any fatigue strength and durability model to a unique form what facilitates the models comparison ...
Mikhailov, SE, Namestnikova, IV
core   +1 more source

Search for weak M1 transitions in $^{48}$Ca with inelastic proton scattering

open access: yes, 2017
The spinflip M1 resonance in the doubly magic nucleus $^{48}$Ca, dominated by a single transition, serves as a reference case for the quenching of spin-isospin modes in nuclei.
Birkhan, J.   +7 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Material's Strength Analysis of the Coupling Node of Axle of the Truck Trailer. [PDF]

open access: yesMaterials (Basel), 2023
Decker Ž   +7 more
europepmc   +1 more source

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