Results 91 to 100 of about 1,451,944 (303)

Graphical analysis-based calculation method of concrete strength

open access: yesAIP Advances
This study established a three-dimensional random spherical aggregate model of concrete. Models with various volume contents of coarse aggregate were sliced, and slice areas were statistically analyzed. To study the effects of the coarse aggregate volume
Xiaohui Wang   +4 more
doaj   +1 more source

A Shear Strength Model for a Subsidence Backfill Body Based on Adhesion Friction Theory

open access: yesAdvances in Civil Engineering, 2020
Proper determination of the shear strength of the backfill body used to fill the subsidence is the basis for subsidence restoration and the stability analysis of materials.
Lei Liu   +4 more
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Calculation of sub-surface-initiated fatigue fractures in gears [PDF]

open access: yes, 2019
Power-transmitting gears are typically heat-treated, most often case-hardened, to improve the fatigue strength and therefore to ensure higher fatigue life.
Müller, Daniel   +2 more
core  

Technic Characteristics of the Vehicle Bogie of the Second Phase of Wuhan Rail Transit Line 1

open access: yes机车电传动, 2011
This paper introduced technic characteristics of vehicle bogie of the second phase of Wuhan rail transit line 1, which included bogie structure, main characteristic and technic parameters.
李涛, 陈喜红, 卜旦霞, 刘晖霞
doaj  

Shell-model calculation of strength functions

open access: yesPhysics Letters B, 1980
Abstract We show how shell-model calculations that use the Lanczos method may be extended to provide information about the distribution of the initial vector among the eigenstates of the system, without actually calculating these eigenstates. By choosing the initial state appropriately this allows, for example, the calculation of the distribution of ...
R.R. Whitehead, A. Watt, D. Kelvin
openaire   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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