Results 91 to 100 of about 347,905 (307)

A Shear Strength Model for a Subsidence Backfill Body Based on Adhesion Friction Theory

open access: yesAdvances in Civil Engineering, 2020
Proper determination of the shear strength of the backfill body used to fill the subsidence is the basis for subsidence restoration and the stability analysis of materials.
Lei Liu   +4 more
doaj   +1 more source

The relationship between the compressive strength of cement mortar and the chemical composition and fineness of cement

open access: yes, 1993
Includes bibliography.The purpose of this research was to determine a method whereby predictions of compressive strength could be made with regard to the chemical composition and fineness of Portland cement.
James, S D
core  

Numerical Calculation of High-Strength-Steel Saddle Plate Forming Suitable for Lightweight Construction of Ships

open access: yes, 2023
With the demand for construction of lightweight ships and polar ships, high-strength steel is increasingly applied in shipbuilding. There are a large number of complex curved plates to be processed in ship construction.
Shun Wang   +5 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Local and non-local normalised equivalent strain functionals for cyclic fatigue

open access: yes, 2004
The concept of Cyclic Normalised Equivalent Strain Functionals (CNESnFs) suitable for lowcyclic fatigue is developed in this paper. It reduces any fatigue strength and durability model to a unique form what facilitates the models comparison ...
Mikhailov, SE   +3 more
core  

FATIGUE STRENGTH PREDICTION OF RAILWAY AXLE SPECIMEN WITH SURFACE NOTCH BY TCD

open access: yes, 2022
This paper, based on theory of critical distance(TCD), carried out a research on the fatigue strength prediction of axle specimens with surface notch. The fatigue limit of smooth specimens, specimens with V-shaped surface notch, and specimens with hole ...
ZENG DongFang   +4 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Calculation of the rotational strengths of mononucleosides [PDF]

open access: yesJournal of the American Chemical Society, 1971
Teng, Nelson N.H.   +2 more
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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