Results 111 to 120 of about 6,309,861 (384)
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Calculation of the rotational strengths of mononucleosides [PDF]
Journal of the American Chemical Society, 1971 Teng, Nelson N.H. +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
Semiclassical calculation of oscillator-strengths
Journal de Physique, 1989 Because they play a fundamental role in the calculation of bound electron stopping-powers, photon mean free paths and electron impact-excitation cross-sections, there is a need for a convenient method to calculate oscillator strengths for highly charged ions.
More, R.M., Warren, K.H.
openaire +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
The Strength of Non-Perturbative Effects in Matrix Models and String Effective Lagrangians [PDF]
, 1994 We present a summary of the results of an explicit calculation of the strength of non-perturbative interactions in matrix models and string effective Lagrangians.
Brustein, R., Faux, M., Ovrut, B.
core +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
COMPARISON BETWEEN HB AND AGMA BEVEL GEAR STRENGTH CALCULATION STANDARD
Jixie qiangdu, 2015 In this paper similarities and differences in Bearing Capacity Calculation of Aviation Bevel Gears（ HB / Z89.1 HB / Z89.4-85） and Rating the Pitting Resistance and Bending Strength of Generated Straight Bevel,Zerol Bevel and Spiral Bevel Gear Teeth（ ANSI
LI XiangYu, LIU ShaoJun
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