Results 51 to 60 of about 1,520,419 (296)

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Caracterización estructural de la madera de Pinus radiata D. Don del país vasco (España) acorde a las modificaciones normativas

open access: yesMaderas: Ciencia y Tecnología, 2014
En las últimas décadas en Europa se ha promovido la promulgación de Códigos de Práctica, Directivas y Normas Armonizadas de obligado cumplimiento para los países miembros, que afectan a la madera en la construcción y que son imprescindibles para ...
Hermoso E.   +2 more
doaj  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

CARACTERIZACIÓN ESTRUCTURAL DE LA MADERA DE Pinus radiata D. Don DEL PAÍS VASCO (ESPAÑA) ACORDE A LAS MODIFICACIONES NORMATIVAS STRUCTURAL CHARACTERIZATION OF Pinus radiata D. Don TIMBER FROM PAÍS VASCO (SPAIN) ACCORDING TO STANDARD MODIFICATIONS

open access: yesMaderas: Ciencia y Tecnología, 2007
En las últimas décadas en Europa se ha promovido la promulgación de Códigos de Práctica, Directivas y Normas Armonizadas de obligado cumplimiento para los países miembros, que afectan a la madera en la construcción y que son imprescindibles para ...
E Hermoso   +2 more
doaj  

Shear strength properties of wet granular materials

open access: yes, 2006
We investigate shear strength properties of wet granular materials in the pendular state (i.e. the state where the liquid phase is discontinuous) as a function of water content. Sand and glass beads were wetted and tested in a direct shear cell and under
C. Thornton   +13 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

THE EFFECTS OF 12-WEEK ISOKINETIC TRAINING ON KNEE STABILIZERS STRENGTH AND THE EFFICIENCY OF THE PERFORMANCE OF GYMNASTICS VAULTS

open access: yesScience of Gymnastics Journal, 2023
The aim of the research was to examine the effects of isokinetic training on knee stabilizer strength, and whether this increases the efficiency of performing basic gymnastics vaults.
Adis Tabaković   +2 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Ab-initio calculation of the effective on-site Coulomb interaction parameters for half-metallic magnets [PDF]

open access: yes, 2013
Correlation effects play an important role in the electronic structure of half-metallic (HM) magnets. In particular, they give rise to non-quasiparticle states above (or below) the Fermi energy at finite temperatures that reduce the spin polarization and,
Blügel, Stefan   +3 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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